Tirzepatid VS Semaglutid

Tirzepatid und Semaglutid sind beides injizierbare Medikamente, die zur Gewichtsabnahme und -abnahme verwendet werden. 2 Diabetes-Management, Sie unterscheiden sich jedoch in ihren Wirkmechanismen und ihrer Wirksamkeit. Hier ist ein Vergleich der beiden Medikamente:

Mechanism of Action​

Tirzepatide:

• Duales glukoseabhängiges insulinotropes Polypeptid (GIP) und Glucagon-ähnliches Peptid-1 (GLP-1) Rezeptor-Agonist
• Activates both GIP and GLP-1 receptors

Semaglutide:

• Selective GLP-1 receptor agonist
• Activates only GLP-1 receptors

Effectiveness for Weight Loss​

Tirzepatide:

• Associated with greater weight loss compared to semaglutide
• In a study of adults with overweight or obesity:
  • Patients were 1.76 times more likely to achieve ≥5% weight loss
  • 2.54 times more likely to achieve ≥10% weight loss
  • 3.24 times more likely to achieve ≥15% weight loss compared to semaglutide

Semaglutide:

• Effective for weight loss, but generally less so than tirzepatide
• Approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition

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